In Stock
MOTS-C vial
MOT-06MOTS-c (Mitochondrial Peptide)

Optimize Your Cellular Energy

MOTS-C

Mitochondrial Metabolism Reset For Stubborn Weight And Energy.

99%+ Purity
Partnered with compliant and licensed U.S. compounding pharmacies
Compounded under strict cGMP protocols

Choose Your Supply

*Price includes medication only, if prescribed. An active OxyTides Membership is required ($39 first month, then $99/month). Membership does not guarantee a prescription.

  • Fat loss support

    Improves metabolic efficiency and fat oxidation.

  • Better insulin sensitivity

    Supports stable blood sugar across the day.

  • Increased energy

    Higher mitochondrial output translates to steadier energy.

  • Breaks weight plateaus

    Useful when GLP-1 results have stalled.

Compounded in the U.S.A
FSA & HSA Eligible
The Life You're Building

MOTS-C: Mitochondrial Metabolism Reset For Stubborn Weight And Energy.

MOTS-c is a mitochondrial-derived peptide that improves insulin sensitivity, fat oxidation, and metabolic efficiency. Unlike GLP-1s, it works at the cellular energy level rather than suppressing appetite. 99%+ Purity. Partnered with compliant and licensed U.S. compounding pharmacies. Compounded under strict cGMP protocols.

The Science

How MOTS-C Actually Works

MOTS-c is a 16-amino-acid peptide encoded in mitochondrial DNA. It activates AMPK in skeletal muscle, improving glucose uptake, fatty-acid oxidation, and insulin sensitivity — essentially a mitochondrial 'exercise mimetic.'

Half-life
~hours sub-Q
Target
AMPK / muscle
Origin
2015 (Lee et al.)
Route
Weekly Sub-Q

mtDNA

Mito-encoded peptide

AMPK

Primary pathway

16 AA

Peptide length

Exercise mimetic

Activates the same AMPK pathway upregulated by endurance training.

Insulin sensitizer

Improves glucose homeostasis and reverses diet-induced insulin resistance in animal models.

Declines with age

Endogenous MOTS-c levels drop with age, correlating with metabolic decline.

Selected Research
  • The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasisCell Metabolism · 2015
  • MOTS-c, an exercise-induced mitochondrial-encoded regulatorNature Communications · 2021

Educational summary. Not medical advice. Therapy outcomes vary and require physician evaluation.

Overview

Why MOTS-C

MOTS-c is a mitochondrial-derived peptide that improves insulin sensitivity, fat oxidation, and metabolic efficiency. Unlike GLP-1s, it works at the cellular energy level rather than suppressing appetite. 99%+ Purity. Partnered with compliant and licensed U.S. compounding pharmacies. Compounded under strict cGMP protocols.

Dosing
Weekly Sub-Q
Support
MD-Supervised Titration
Peptide
MOTS-c (Mitochondrial Peptide)
Starting Price
$270 per month

Hit your health goals safely & affordably in 3 simple steps

Submit your application and meet with a doctor

Step

1

Complete a 3-minute medical intake and optional lab panel.

Get your protocol delivered at home

Step

2

A licensed physician reviews your goals and biomarkers.

Stay on track with 24/7 support and ongoing care

Step

3

Your protocol is compounded by a 503A/503B regulated pharmacy.

Questions

Frequently Asked

GLP-1s suppress appetite and slow gastric emptying. MOTS-c works at the mitochondrial level to improve fat oxidation and insulin sensitivity, preserving muscle and energy.
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Ready to start MOTS-C?

Physician-prescribed, FDA-regulated pharmacy. No commitment to continue.